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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 708351
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Kdm3a
Name: lysine demethylase 3A
Acc ID: CHEBI:27958
Term: cocaine
Definition: A tropane alkaloid obtained from leaves of the South American shrub Erythroxylon coca.
Chemical ID: MESH:D003042
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Kdm3aincreases expressionISOKdm3a (Mus musculus)6480464CTDCocaine results in increased expression of KDM3A mRNAPMID:18355967
Kdm3amultiple interactionsISOKdm3a (Mus musculus)6480464CTDFOS protein mutant form inhibits the reaction [Cocaine results in increased expression of KDM3A mRNA]PMID:18355967
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