Send us a Message

Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   


RGD ID: 619837
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Neo1
Name: neogenin 1
Acc ID: CHEBI:27958
Term: cocaine
Definition: A tropane alkaloid obtained from leaves of the South American shrub Erythroxylon coca.
Chemical ID: MESH:D003042
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Neo1multiple interactionsISONeo1 (Mus musculus)6480464CTD[[Cocaine results in increased phosphorylation of and results in increased activity of MAPK1 protein] which results in increased expression of FOS protein] which affects the expression of NEO1 protein; Cocaine promotes the reaction [DRD1 protein results in increased expression of NEO1 protein]; Cocaine promotes the reaction [DRD3 protein results in decreased expression of NEO1 protein]PMID:15056714
Go Back to source page   Continue to Ontology report