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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3694
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Slc18a2
Name: solute carrier family 18 member A2
Acc ID: CHEBI:27958
Term: cocaine
Definition: A tropane alkaloid obtained from leaves of the South American shrub Erythroxylon coca.
Chemical ID: MESH:D003042
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Slc18a2increases expressionEXP 6480464CTDCocaine results in increased expression of SLC18A2 proteinPMID:25100957
Slc18a2affects response to substanceISOSlc18a2 (Mus musculus)6480464CTDSLC18A2 protein affects the susceptibility to CocainePMID:12716422
Slc18a2decreases expressionISOSLC18A2 (Homo sapiens)6480464CTDCocaine results in decreased expression of SLC18A2 proteinPMID:12505801
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