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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3054
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Mbp
Name: myelin basic protein
Acc ID: CHEBI:27958
Term: cocaine
Definition: A tropane alkaloid obtained from leaves of the South American shrub Erythroxylon coca.
Chemical ID: MESH:D003042
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Mbpdecreases expressionEXP 6480464CTDCocaine results in decreased expression of MBP proteinPMID:19217266
Mbpdecreases expressionISOMBP (Homo sapiens)6480464CTDCocaine results in decreased expression of MBP mRNA; Cocaine results in decreased expression of MBP proteinPMID:15009677
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