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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2744
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Grm3
Name: glutamate metabotropic receptor 3
Acc ID: CHEBI:27958
Term: cocaine
Definition: A tropane alkaloid obtained from leaves of the South American shrub Erythroxylon coca.
Chemical ID: MESH:D003042
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Grm3affects expressionEXP 6480464CTDCocaine affects the expression of GRM3 proteinPMID:19105975
Grm3increases activityEXP 6480464CTDCocaine results in increased activity of GRM3 proteinPMID:20416862
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