Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2325376
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Mir212
Name: microRNA 212
Acc ID: CHEBI:27958
Term: cocaine
Definition: A tropane alkaloid obtained from leaves of the South American shrub Erythroxylon coca.
Chemical ID: MESH:D003042
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Mir212increases expressionEXP 6480464CTDCocaine results in increased expression of MIR212 mRNA; Cocaine results in increased expression of MIR212 proteinPMID:20613834 PMID:20711185
Mir212multiple interactionsEXP 6480464CTD[[Cocaine results in increased expression of MIR212 mRNA] which results in increased activity of RAF1 protein] which results in increased expression of CRTC1 protein; [Cocaine results in increased expression of MIR212 mRNA] which results in increased activity of RAF1 protein; Cocaine affects the reaction [MIR212 protein affects the expression of BDNF protein]PMID:20613834 PMID:20711185
Mir212multiple interactionsISOMIR212 (Homo sapiens)6480464CTDMECP2 mRNA inhibits the reaction [Cocaine results in increased expression of MIR212 protein]PMID:20711185
Go Back to source page   Continue to Ontology report