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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 731060
Species: Mus musculus
RGD Object: Gene
Symbol: Rhoa
Name: ras homolog family member A
Acc ID: CHEBI:27928
Term: parathion
Definition: An organothiophosphate insecticide that has formula C10H14NO5PS.
Chemical ID: MESH:D010278
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Rhoaincreases expressionISORHOA (Homo sapiens)6480464CTDParathion results in increased expression of RHOA proteinPMID:17390078 PMID:17622325
Rhoamultiple interactionsISORHOA (Homo sapiens)6480464CTD[Parathion co-treated with Estradiol] results in increased expression of RHOA protein; Atropine inhibits the reaction [Parathion results in increased expression of RHOA protein]PMID:17390078 PMID:17622325
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