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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 620349
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Ptgs2
Name: prostaglandin-endoperoxide synthase 2
Acc ID: CHEBI:27924
Term: phenylhydrazine
Definition: A phenylhydrazine that is the monophenyl derivative of hydrazine.
Chemical ID: MESH:C030299
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ptgs2increases expressionISOPtgs2 (Mus musculus)6480464CTDphenylhydrazine results in increased expression of PTGS2 proteinPMID:30626086 PMID:31323261
Ptgs2multiple interactionsISOPtgs2 (Mus musculus)6480464CTDPlant Extracts inhibits the reaction [phenylhydrazine results in increased expression of PTGS2 protein]; SESN2 protein inhibits the reaction [phenylhydrazine results in increased expression of PTGS2 protein]PMID:30626086 PMID:31323261
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