GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Timd2 | decreases response to substance | ISO | Timd2 (Mus musculus) | 6480464 | CTD | TIMD2 results in decreased susceptibility to Cisplatin | PMID:20702592 | Timd2 | multiple interactions | ISO | Timd2 (Mus musculus) | 6480464 | CTD | TIMD2 inhibits the reaction [Cisplatin results in increased expression of IL1B mRNA]; TIMD2 inhibits the reaction [Cisplatin results in increased expression of IL6 mRNA]; TIMD2 inhibits the reaction [Cisplatin results in increased expression of TGFB1 mRNA]; TIMD2 inhibits the reaction [Cisplatin results in increased expression of TNF mRNA]; TIMD2 inhibits the reaction [Cisplatin results in increased expression of TRP53 protein]; TIMD2 promotes the reaction [Cisplatin results in increased expression of CASP3 protein modified form]; TIMD2 promotes the reaction [Cisplatin results in increased expression of CCL2 mRNA]; TIMD2 promotes the reaction [Cisplatin results in increased expression of CCL5 mRNA] | PMID:20702592 | |
Go Back to source page | Continue to Ontology report |