GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | HSPA1A | increases expression | EXP | | 6480464 | CTD | Cisplatin results in increased expression of HSPA1A mRNA | PMID:19561079 PMID:27392435 | HSPA1A | multiple interactions | EXP | | 6480464 | CTD | [Cisplatin co-treated with jinfukang] results in increased expression of HSPA1A mRNA; Cisplatin affects the reaction [Piroxicam results in decreased expression of HSPA1A mRNA] | PMID:21858171 PMID:27392435 | HSPA1A | decreases expression | ISO | Hspa1a (Rattus norvegicus) | 6480464 | CTD | Cisplatin results in decreased expression of HSPA1A protein | PMID:12690470 | HSPA1A | increases expression | ISO | Hspa1a (Rattus norvegicus) | 6480464 | CTD | Cisplatin results in increased expression of HSPA1A mRNA | PMID:18172885 PMID:22023808 | HSPA1A | multiple interactions | ISO | Hspa1a (Rattus norvegicus) | 6480464 | CTD | sodium arsenite inhibits the reaction [Cisplatin results in decreased expression of HSPA1A protein]; uranyl acetate inhibits the reaction [Cisplatin results in decreased expression of HSPA1A protein] | PMID:12690470 | |
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