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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 730821
Species: Homo sapiens
RGD Object: Gene
Symbol: MMP2
Name: matrix metallopeptidase 2
Acc ID: CHEBI:27889
Term: lead(0)
Definition: An elemental lead that has formula Pb.
Chemical ID: MESH:D007854
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
MMP2increases expressionISOMmp2 (Rattus norvegicus)6480464CTDLead results in increased expression of MMP2 mRNAPMID:18836702
MMP2multiple interactionsISOMmp2 (Rattus norvegicus)6480464CTDDoxycycline inhibits the reaction [Lead results in increased expression of and results in increased activity of MMP2 protein]; Lead results in increased expression of and results in increased activity of MMP2 proteinPMID:18836702
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