GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Gsk3b | affects splicing | ISO | GSK3B (Homo sapiens) | 6480464 | CTD | Lead affects the splicing of GSK3B mRNA | PMID:28903495 | Gsk3b | multiple interactions | ISO | Gsk3b (Mus musculus) | 6480464 | CTD | [lead acetate results in increased abundance of Lead] which results in decreased phosphorylation of GSK3B protein; [lead nitrate results in increased abundance of Lead] which results in decreased phosphorylation of GSK3B protein; icaritin inhibits the reaction [[lead nitrate results in increased abundance of Lead] which results in decreased phosphorylation of GSK3B protein] | PMID:30731080 PMID:37436718 | | ||||||||||||||||||||||
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