GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Mapt | affects phosphorylation | EXP | | 6480464 | CTD | Lead affects the phosphorylation of MAPT protein | PMID:22342405 | Mapt | increases phosphorylation | ISO | Mapt (Mus musculus) | 6480464 | CTD | Lead results in increased phosphorylation of MAPT protein | PMID:31539617 | Mapt | multiple interactions | ISO | Mapt (Mus musculus) | 6480464 | CTD | [lead acetate results in increased abundance of Lead] which results in increased phosphorylation of MAPT protein; fisetin inhibits the reaction [Lead results in increased phosphorylation of MAPT protein] | PMID:31539617 PMID:31730887 PMID:32058320 | |
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