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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 69096
Species: Mus musculus
RGD Object: Gene
Symbol: Tgfb1
Name: transforming growth factor, beta 1
Acc ID: CHEBI:27889
Term: lead(0)
Definition: An elemental lead that has formula Pb.
Chemical ID: MESH:D007854
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Tgfb1decreases expressionEXP 6480464CTDLead results in decreased expression of TGFB1 proteinPMID:34742682
Tgfb1multiple interactionsEXP 6480464CTD[[lead acetate results in increased abundance of Lead] co-treated with [IL4 protein co-treated with IL13 protein]] results in increased expression of TGFB1 protein; Dietary Fats promotes the reaction [Lead results in decreased expression of TGFB1 protein]; Lead promotes the reaction [Dietary Fats results in decreased expression of TGFB1 protein]PMID:34352350 PMID:34742682
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