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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 68631
Species: Mus musculus
RGD Object: Gene
Symbol: Dlg4
Name: discs large MAGUK scaffold protein 4
Acc ID: CHEBI:27889
Term: lead(0)
Definition: An elemental lead that has formula Pb.
Chemical ID: MESH:D007854
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Dlg4decreases expressionEXP 6480464CTDLead results in decreased expression of DLG4 proteinPMID:31539617
Dlg4multiple interactionsEXP 6480464CTD[lead acetate results in increased abundance of Lead] which results in decreased expression of DLG4 mRNA; [lead acetate results in increased abundance of Lead] which results in decreased expression of DLG4 protein; fisetin inhibits the reaction [Lead results in decreased expression of DLG4 protein]PMID:26660114 PMID:31539617
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