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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 621531
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Gria1
Name: glutamate ionotropic receptor AMPA type subunit 1
Acc ID: CHEBI:27889
Term: lead(0)
Definition: An elemental lead that has formula Pb.
Chemical ID: MESH:D007854
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
multiple interactionsEXP 6480464CTD[Lead co-treated with Tetrodotoxin] results in increased expression of [GRIA1 protein binds to GRIA2 protein]

PMID:29939358
affects splicingISORGD:7315476480464CTDLead affects the splicing of GRIA1 mRNA

PMID:28903495
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.