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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 11334
Species: Mus musculus
RGD Object: Gene
Symbol: Sp1
Name: trans-acting transcription factor 1
Acc ID: CHEBI:27889
Term: lead(0)
Definition: An elemental lead that has formula Pb.
Chemical ID: MESH:D007854
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Sp1multiple interactionsEXP 6480464CTD[[lead chloride results in increased abundance of Lead] co-treated with [sodium arsenite results in increased abundance of Arsenic]] results in increased expression of SP1 protein; [[lead chloride results in increased abundance of Lead] which co-treated with methylmercuric chloride] results in increased expression of SP1 proteinPMID:32179164
Sp1increases expressionISOSP1 (Homo sapiens)6480464CTDLead results in increased expression of SP1 proteinPMID:22272629
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