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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 10398
Species: Mus musculus
RGD Object: Gene
Symbol: Crp
Name: C-reactive protein, pentraxin-related
Acc ID: CHEBI:27889
Term: lead(0)
Definition: An elemental lead that has formula Pb.
Chemical ID: MESH:D007854
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Crpincreases expressionISOCRP (Homo sapiens)6480464CTDLead results in increased expression of CRP proteinPMID:23484121
Crpmultiple interactionsISOCRP (Homo sapiens)6480464CTD[GSTM1 gene mutant form co-treated with GSTT1 gene mutant form] promotes the reaction [Lead results in increased expression of CRP protein]; GSTM1 gene mutant form promotes the reaction [Lead results in increased expression of CRP protein]; GSTP1 gene polymorphism affects the reaction [Lead results in increased expression of CRP protein]; GSTT1 gene mutant form promotes the reaction [Lead results in increased expression of CRP protein]PMID:23484121
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