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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1313498
Species: Homo sapiens
RGD Object: Gene
Symbol: PPM1D
Name: protein phosphatase, Mg2+/Mn2+ dependent 1D
Acc ID: CHEBI:27882
Term: (S)-colchicine
Definition: A colchicine that has (S)-configuration. It is a secondary metabolite, has anti-inflammatory properties and is used to treat gout, crystal-induced joint inflammation, familial Mediterranean fever, and many other conditions.
Chemical ID: MESH:D003078
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
PPM1Ddecreases expressionEXP 6480464CTDColchicine results in decreased expression of PPM1D mRNAPMID:24211769
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