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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 737312
Species: Homo sapiens
RGD Object: Gene
Symbol: AGER
Name: advanced glycosylation end-product specific receptor
Acc ID: CHEBI:27881
Term: resveratrol
Definition: A stilbenol that is stilbene in which the phenyl groups are substituted at positions 3, 5, and 4' by hydroxy groups.
Chemical ID: MESH:C059514
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
AGERdecreases expressionEXP 6480464CTDresveratrol results in decreased expression of AGER proteinPMID:20372816
AGERmultiple interactionsEXP 6480464CTD[2-chloro-5-nitrobenzanilide binds to and results in decreased activity of PPARG protein] inhibits the reaction [resveratrol results in increased expression of AGER protein]; [resveratrol results in increased activity of PPARG protein] which results in decreased expression of AGER protein; resveratrol inhibits the reaction [ALB protein modified form results in increased expression of AGER protein]PMID:20372816 PMID:23936610
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