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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 736615
Species: Homo sapiens
RGD Object: Gene
Symbol: IFNB1
Name: interferon beta 1
Acc ID: CHEBI:27881
Term: resveratrol
Definition: A stilbenol that is stilbene in which the phenyl groups are substituted at positions 3, 5, and 4' by hydroxy groups.
Chemical ID: MESH:C059514
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
IFNB1decreases expressionEXP 6480464CTDresveratrol results in decreased expression of IFNB1 mRNAPMID:23224687
IFNB1multiple interactionsEXP 6480464CTD[Plant Extracts co-treated with Resveratrol] results in decreased expression of IFNB1 mRNAPMID:23557933
IFNB1multiple interactionsISOIfnb1 (Mus musculus)6480464CTDresveratrol inhibits the reaction [Lipopolysaccharides results in increased expression of IFNB1 mRNA]; resveratrol inhibits the reaction [Poly I-C results in increased expression of IFNB1 mRNA]; resveratrol inhibits the reaction [TICAM1 protein results in increased expression of IFNB1 mRNA]PMID:16116226
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