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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 736585
Species: Homo sapiens
RGD Object: Gene
Symbol: SLC9A1
Name: solute carrier family 9 member A1
Acc ID: CHEBI:27881
Term: resveratrol
Definition: A stilbenol that is stilbene in which the phenyl groups are substituted at positions 3, 5, and 4' by hydroxy groups.
Chemical ID: MESH:C059514
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
SLC9A1increases expressionEXP 6480464CTDresveratrol results in increased expression of SLC9A1 proteinPMID:21191669
SLC9A1multiple interactionsEXP 6480464CTD[resveratrol results in increased expression of SLC9A1 protein] which results in increased uptake of Sodium ChloridePMID:21191669
SLC9A1decreases expressionISOSlc9a1 (Mus musculus)6480464CTDresveratrol results in decreased expression of SLC9A1 mRNA; resveratrol results in decreased expression of SLC9A1 proteinPMID:18951995
SLC9A1decreases expressionISOSlc9a1 (Rattus norvegicus)6480464CTDresveratrol results in decreased expression of SLC9A1 mRNA; resveratrol results in decreased expression of SLC9A1 proteinPMID:18951995
SLC9A1multiple interactionsISOSlc9a1 (Mus musculus)6480464CTDCASP3 protein affects the reaction [resveratrol results in decreased expression of SLC9A1 mRNA]; CASP3 protein affects the reaction [resveratrol results in decreased expression of SLC9A1 protein]; CASP6 protein affects the reaction [resveratrol results in decreased expression of SLC9A1 mRNA]; CASP6 protein affects the reaction [resveratrol results in decreased expression of SLC9A1 protein]; CAT protein affects the reaction [resveratrol results in decreased expression of SLC9A1 mRNA]; CAT protein affects the reaction [resveratrol results in decreased expression of SLC9A1 protein]; Mercaptoethanol affects the reaction [resveratrol results in decreased expression of SLC9A1 mRNA]; Mercaptoethanol affects the reaction [resveratrol results in decreased expression of SLC9A1 protein]; Phenanthrolines affects the reaction [resveratrol results in decreased expression of SLC9A1 mRNA]; Phenanthrolines affects the reaction [resveratrol results in decreased expression of SLC9A1 protein]PMID:18951995
SLC9A1multiple interactionsISOSlc9a1 (Rattus norvegicus)6480464CTD[resveratrol results in increased abundance of Hydrogen Peroxide] which results in decreased expression of SLC9A1 protein; benzoylcarbonyl-aspartyl-glutamyl-valyl-aspartyl-fluoromethyl ketone inhibits the reaction [resveratrol results in decreased expression of SLC9A1 protein]; CASP3 protein affects the reaction [resveratrol results in decreased expression of SLC9A1 protein]; CASP6 protein affects the reaction [resveratrol results in decreased expression of SLC9A1 protein]; CAT protein inhibits the reaction [resveratrol results in decreased expression of SLC9A1 protein]PMID:18951995
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