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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 735659
Species: Homo sapiens
RGD Object: Gene
Symbol: SNAI2
Name: snail family transcriptional repressor 2
Acc ID: CHEBI:27881
Term: resveratrol
Definition: A stilbenol that is stilbene in which the phenyl groups are substituted at positions 3, 5, and 4' by hydroxy groups.
Chemical ID: MESH:C059514
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
SNAI2decreases expressionEXP 6480464CTDresveratrol results in decreased expression of SNAI2 mRNA; resveratrol results in decreased expression of SNAI2 proteinPMID:21304978 PMID:22692956 PMID:26310874
SNAI2multiple interactionsEXP 6480464CTD[Plant Extracts co-treated with Resveratrol] results in decreased expression of SNAI2 mRNA; Resveratrol inhibits the reaction [Fluorouracil results in increased expression of SNAI2 protein]; Resveratrol inhibits the reaction [TGFB1 protein results in increased expression of SNAI2 mRNA]; Resveratrol inhibits the reaction [TGFB1 protein results in increased expression of SNAI2 protein]PMID:23146760 PMID:23557933 PMID:25884904 PMID:26310874
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