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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 733896
Species: Mus musculus
RGD Object: Gene
Symbol: Hspd1
Name: heat shock protein 1 (chaperonin)
Acc ID: CHEBI:27881
Term: resveratrol
Definition: A stilbenol that is stilbene in which the phenyl groups are substituted at positions 3, 5, and 4' by hydroxy groups.
Chemical ID: MESH:C059514
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Hspd1increases expressionEXP 6480464CTDresveratrol results in increased expression of HSPD1 mRNAPMID:22610192
Hspd1affects expressionISOHSPD1 (Homo sapiens)6480464CTDresveratrol affects the expression of HSPD1 proteinPMID:22234583 PMID:23255428
Hspd1decreases expressionISOHSPD1 (Homo sapiens)6480464CTDresveratrol results in decreased expression of HSPD1 proteinPMID:24170104
Hspd1multiple interactionsISOHspd1 (Rattus norvegicus)6480464CTDresveratrol inhibits the reaction [Adenosine Triphosphate results in increased expression of HSPD1 protein]; resveratrol promotes the reaction [Diethylhexyl Phthalate results in increased expression of HSPD1 mRNA]PMID:16178011 PMID:26361869
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