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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 733453
Species: Homo sapiens
RGD Object: Gene
Symbol: FABP4
Name: fatty acid binding protein 4
Acc ID: CHEBI:27881
Term: resveratrol
Definition: A stilbenol that is stilbene in which the phenyl groups are substituted at positions 3, 5, and 4' by hydroxy groups.
Chemical ID: MESH:C059514
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
FABP4affects secretionEXP 6480464CTDresveratrol affects the secretion of FABP4 proteinPMID:24802182
FABP4decreases expressionEXP 6480464CTDresveratrol results in decreased expression of FABP4PMID:21852083
FABP4decreases expressionISOFabp4 (Mus musculus)6480464CTDResveratrol results in decreased expression of FABP4 mRNA; Resveratrol results in decreased expression of FABP4 proteinPMID:16813520 PMID:18555852 PMID:23525482 PMID:25761413 PMID:30920877
FABP4multiple interactionsISOFabp4 (Mus musculus)6480464CTDRosiglitazone inhibits the reaction [Resveratrol results in decreased expression of FABP4 mRNA]; splitomicin promotes the reaction [Resveratrol results in decreased expression of FABP4 mRNA]; splitomicin promotes the reaction [Resveratrol results in decreased expression of FABP4 protein]PMID:23525482 PMID:30920877
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