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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 69267
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Slc5a5
Name: solute carrier family 5 member 5
Acc ID: CHEBI:27881
Term: resveratrol
Definition: A stilbenol that is stilbene in which the phenyl groups are substituted at positions 3, 5, and 4' by hydroxy groups.
Chemical ID: MESH:C059514
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Slc5a5decreases expressionEXP 6480464CTDresveratrol results in decreased expression of SLC5A5; resveratrol results in decreased expression of SLC5A5 proteinPMID:28668442
Slc5a5increases expressionISOSLC5A5 (Homo sapiens)6480464CTDresveratrol results in increased expression of SLC5A5 mRNAPMID:21738342 PMID:23594881
Slc5a5multiple interactionsISOSLC5A5 (Homo sapiens)6480464CTDNOTCH1 mutant form inhibits the reaction [resveratrol results in increased expression of SLC5A5 mRNA]PMID:23594881
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