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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 69247
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Kcnj11
Name: potassium inwardly-rectifying channel, subfamily J, member 11
Acc ID: CHEBI:27881
Term: resveratrol
Definition: A stilbenol that is stilbene in which the phenyl groups are substituted at positions 3, 5, and 4' by hydroxy groups.
Chemical ID: MESH:C059514
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Kcnj11affects response to substanceISOKcnj11 (Mus musculus)6480464CTDKCNJ11 protein affects the susceptibility to resveratrolPMID:24498880
Kcnj11increases activityISOKcnj11 (Mus musculus)6480464CTDresveratrol results in increased activity of KCNJ11 proteinPMID:24498880
Kcnj11increases expressionISOKcnj11 (Mus musculus)6480464CTDresveratrol results in increased expression of KCNJ11 proteinPMID:24498880
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