Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 621720
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Gpt
Name: glutamic--pyruvic transaminase
Acc ID: CHEBI:27881
Term: resveratrol
Definition: A stilbenol that is stilbene in which the phenyl groups are substituted at positions 3, 5, and 4' by hydroxy groups.
Chemical ID: MESH:C059514
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Gptincreases expressionEXP 6480464CTDresveratrol results in increased expression of GPT proteinPMID:15748624
Gptmultiple interactionsEXP 6480464CTD[raspberry ketone co-treated with Resveratrol] inhibits the reaction [Carbon Tetrachloride results in increased expression of GPT protein]; [Resveratrol co-treated with Niacinamide] inhibits the reaction [[Aflatoxin B1 co-treated with Ethanol] results in increased expression of GPT protein]; Resveratrol analog inhibits the reaction [bisphenol A results in increased activity of GPT protein]; Resveratrol inhibits the reaction [[2-cyano-N-((ethylamino)carbonyl)-2-(methoxyimino)acetamide co-treated with mancozeb] results in increased expression of GPT protein]; Resveratrol inhibits the reaction [[Aflatoxin B1 co-treated with Ethanol] results in increased expression of GPT protein]; Resveratrol inhibits the reaction [Carbon Tetrachloride results in increased expression of GPT protein]; Resveratrol inhibits the reaction [chromium hexavalent ion results in increased activity of GPT protein]; Resveratrol inhibits the reaction [Diazinon results in increased expression of GPT protein]; Resveratrol inhibits the reaction [Methotrexate results in increased expression of GPT protein]; Resveratrol inhibits the reaction [Streptozocin results in increased expression of GPT protein]PMID:23424212 PMID:26071184 PMID:32894639 PMID:34067838 PMID:35024197 PMID:35403302 PMID:37009719 PMID:37009748
Gptmultiple interactionsISOGPT (Homo sapiens)6480464CTD[Plant Extracts co-treated with Resveratrol] results in decreased expression of GPT mRNAPMID:23557933
Gptmultiple interactionsISOGpt (Mus musculus)6480464CTDChloroquine inhibits the reaction [resveratrol inhibits the reaction [[Choline deficiency co-treated with Methionine deficiency] results in increased activity of GPT protein]]; resveratrol affects the reaction [Cisplatin results in increased activity of GPT protein]; resveratrol inhibits the reaction [[Choline deficiency co-treated with Methionine deficiency] results in increased activity of GPT protein]PMID:26498332 PMID:28606469
Go Back to source page   Continue to Ontology report