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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 621176
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Scd
Name: stearoyl-CoA desaturase
Acc ID: CHEBI:27881
Term: resveratrol
Definition: A stilbenol that is stilbene in which the phenyl groups are substituted at positions 3, 5, and 4' by hydroxy groups.
Chemical ID: MESH:C059514
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Scdmultiple interactionsEXP 6480464CTDResveratrol inhibits the reaction [T0901317 results in increased expression of SCD1 mRNA]; Resveratrol metabolite inhibits the reaction [T0901317 results in increased expression of SCD1 mRNA]PMID:24633463
Scddecreases expressionISOScd1 (Mus musculus)6480464CTDresveratrol results in decreased expression of SCD1 mRNAPMID:18755807 PMID:24722352
Scdmultiple interactionsISOSCD (Homo sapiens)6480464CTD[Coumestrol co-treated with Resveratrol] results in increased expression of SCD mRNA; Resveratrol inhibits the reaction [T0901317 results in increased expression of SCD mRNA]PMID:19167446 PMID:23651738
Scdmultiple interactionsISOScd1 (Mus musculus)6480464CTDresveratrol inhibits the reaction [Ethanol results in increased expression of SCD1 mRNA]PMID:18755807
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