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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 619802
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Tnfrsf11b
Name: TNF receptor superfamily member 11B
Acc ID: CHEBI:27881
Term: resveratrol
Definition: A stilbenol that is stilbene in which the phenyl groups are substituted at positions 3, 5, and 4' by hydroxy groups.
Chemical ID: MESH:C059514
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Tnfrsf11bincreases expressionISOTnfrsf11b (Mus musculus)6480464CTDresveratrol results in increased expression of TNFRSF11B mRNAPMID:16813520
Tnfrsf11bmultiple interactionsISOTnfrsf11b (Mus musculus)6480464CTDresveratrol inhibits the reaction [Alprostadil results in increased expression of TNFRSF11B mRNA]; resveratrol inhibits the reaction [Alprostadil results in increased secretion of TNFRSF11B protein]; resveratrol inhibits the reaction [Dinoprost results in increased expression of and results in increased secretion of TNFRSF11B protein]; resveratrol inhibits the reaction [Dinoprost results in increased expression of TNFRSF11B mRNA]; resveratrol inhibits the reaction [FGF2 protein results in increased expression of TNFRSF11B mRNA]; resveratrol inhibits the reaction [FGF2 protein results in increased secretion of TNFRSF11B protein]; resveratrol inhibits the reaction [Prostaglandin D2 results in increased expression of TNFRSF11B mRNA]; resveratrol inhibits the reaction [Prostaglandin D2 results in increased secretion of TNFRSF11B protein]PMID:24333336 PMID:24813642 PMID:25290095 PMID:25677506
Tnfrsf11bmultiple interactionsISOTNFRSF11B (Homo sapiens)6480464CTDFulvestrant inhibits the reaction [Resveratrol inhibits the reaction [TNF protein results in increased expression of TNFRSF11B mRNA]]; Resveratrol inhibits the reaction [TNF protein results in increased expression of TNFRSF11B mRNA]PMID:24771768
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