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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3348
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Plcg2
Name: phospholipase C, gamma 2
Acc ID: CHEBI:27881
Term: resveratrol
Definition: A stilbenol that is stilbene in which the phenyl groups are substituted at positions 3, 5, and 4' by hydroxy groups.
Chemical ID: MESH:C059514
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Plcg2multiple interactionsISOPLCG2 (Homo sapiens)6480464CTD[Plant Extracts co-treated with Resveratrol] results in increased expression of PLCG2 mRNA; Resveratrol inhibits the reaction [COL1A1 protein results in increased phosphorylation of PLCG2 protein]PMID:23557933 PMID:26482867
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