GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Hmgb1 | multiple interactions | ISO | Hmgb1 (Mus musculus) | 6480464 | CTD | [resveratrol co-treated with HMGB1 protein] affects the localization of NFE2L2 protein; [resveratrol co-treated with HMGB1 protein] results in increased expression of ABCC5 mRNA; [resveratrol co-treated with HMGB1 protein] results in increased expression of AKR1B10 mRNA; [resveratrol co-treated with HMGB1 protein] results in increased expression of HMOX1 mRNA; [resveratrol co-treated with HMGB1 protein] results in increased expression of NQO1 mRNA; NFE2L2 protein affects the reaction [resveratrol inhibits the reaction [HMGB1 protein results in decreased expression of CDH5 protein]]; resveratrol affects the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of HMGB1 mRNA]; resveratrol inhibits the reaction [HMGB1 protein results in decreased expression of CDH5 protein]; resveratrol inhibits the reaction [HMGB1 protein results in decreased expression of NFE2L2 mRNA]; resveratrol inhibits the reaction [HMGB1 protein results in decreased expression of NFE2L2 protein]; resveratrol inhibits the reaction [HMGB1 protein results in decreased expression of TJP1 protein]; resveratrol inhibits the reaction [lipopolysaccharide, E coli O55-B5 affects the localization of HMGB1 protein]; resveratrol inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of HMGB1 protein] | PMID:24802390 PMID:25651848 PMID:25979658 | Hmgb1 | multiple interactions | ISO | HMGB1 (Homo sapiens) | 6480464 | CTD | [Coumestrol co-treated with Resveratrol] results in increased expression of HMGB1 mRNA; [Plant Extracts co-treated with Resveratrol] results in increased expression of HMGB1 mRNA | PMID:19167446 PMID:23557933 | |
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