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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2507
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Dmd
Name: dystrophin
Acc ID: CHEBI:27881
Term: resveratrol
Definition: A stilbenol that is stilbene in which the phenyl groups are substituted at positions 3, 5, and 4' by hydroxy groups.
Chemical ID: MESH:C059514
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Dmddecreases expressionISODmd (Mus musculus)6480464CTDresveratrol results in decreased expression of DMD mRNAPMID:22610192
Dmdmultiple interactionsISODmd (Mus musculus)6480464CTDresveratrol inhibits the reaction [DMD gene mutant form results in decreased expression of ATP2A2 mRNA]; resveratrol inhibits the reaction [DMD gene mutant form results in increased expression of ACTA2 mRNA]; resveratrol inhibits the reaction [DMD gene mutant form results in increased expression of COL1A1 mRNA]; resveratrol inhibits the reaction [DMD gene mutant form results in increased expression of COL1A2 mRNA]; resveratrol inhibits the reaction [DMD gene mutant form results in increased expression of COL3A1 mRNA]; resveratrol inhibits the reaction [DMD gene mutant form results in increased expression of EP300 protein]; resveratrol inhibits the reaction [DMD gene mutant form results in increased expression of NPPA mRNA]; resveratrol inhibits the reaction [DMD gene mutant form results in increased expression of TGFB1 mRNA]PMID:23297412 PMID:26930420
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