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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2085
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Alb
Name: albumin
Acc ID: CHEBI:27881
Term: resveratrol
Definition: A stilbenol that is stilbene in which the phenyl groups are substituted at positions 3, 5, and 4' by hydroxy groups.
Chemical ID: MESH:C059514
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Albdecreases abundanceEXP 6480464CTDresveratrol results in decreased abundance of ALB proteinPMID:20332614
Albaffects expressionISOAlb (Mus musculus)6480464CTDResveratrol affects the expression of ALB proteinPMID:31116951
Albdecreases secretionISOAlb (Mus musculus)6480464CTDresveratrol results in decreased secretion of ALB proteinPMID:21270273
Albmultiple interactionsISOAlb (Mus musculus)6480464CTDresveratrol inhibits the reaction [Ethanol results in decreased expression of ALB protein]PMID:21086752
Albmultiple interactionsISOALB (Homo sapiens)6480464CTDresveratrol binds to and affects the folding of ALB protein; resveratrol binds to and affects the folding of and results in increased stability of ALB protein; resveratrol inhibits the reaction [ALB protein modified form results in increased activity of NFKB1 protein]; resveratrol inhibits the reaction [ALB protein modified form results in increased activity of RELA protein]; resveratrol inhibits the reaction [ALB protein modified form results in increased expression of AGER protein]; resveratrol inhibits the reaction [ALB protein modified form results in increased expression of IL1B protein]; resveratrol inhibits the reaction [ALB protein modified form results in increased expression of TNF protein]; resveratrol inhibits the reaction [ALB protein modified form results in increased phosphorylation of MAPK1 protein]; resveratrol inhibits the reaction [ALB protein modified form results in increased phosphorylation of MAPK3 protein]PMID:17054386 PMID:17597382 PMID:23936610
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