GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | TFAM | decreases expression | EXP | | 6480464 | CTD | resveratrol results in decreased expression of TFAM mRNA | PMID:12002526 | TFAM | increases expression | EXP | | 6480464 | CTD | resveratrol results in increased expression of TFAM mRNA | PMID:21163946 PMID:21224254 PMID:24041027 PMID:24582596 | TFAM | multiple interactions | EXP | | 6480464 | CTD | 1H-(1,2,4)oxadiazolo(4,3-a)quinoxalin-1-one inhibits the reaction [Resveratrol results in increased expression of TFAM mRNA]; 6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide inhibits the reaction [SIRT1 protein promotes the reaction [Resveratrol results in increased expression of TFAM mRNA]]; [Plant Extracts co-treated with Resveratrol] results in increased expression of TFAM mRNA; Resveratrol inhibits the reaction [Hydrogen Peroxide results in decreased expression of TFAM mRNA]; Resveratrol promotes the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of TFAM mRNA]; SIRT1 protein promotes the reaction [Resveratrol results in increased expression of TFAM mRNA]; tin protoporphyrin IX inhibits the reaction [Resveratrol promotes the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of TFAM mRNA]]; tin protoporphyrin IX inhibits the reaction [Resveratrol results in increased expression of TFAM mRNA] | PMID:21163946 PMID:23557933 PMID:23859249 PMID:24041027 | TFAM | increases expression | ISO | Tfam (Rattus norvegicus) | 6480464 | CTD | Resveratrol results in increased expression of TFAM; Resveratrol results in increased expression of TFAM mRNA | PMID:20429690 PMID:23790948 PMID:32619457 | TFAM | increases expression | ISO | Tfam (Mus musculus) | 6480464 | CTD | resveratrol results in increased expression of TFAM mRNA | PMID:17438283 PMID:21224254 PMID:22610192 PMID:24041027 | TFAM | multiple interactions | ISO | Tfam (Rattus norvegicus) | 6480464 | CTD | Resveratrol affects the reaction [Benzo(a)pyrene affects the expression of TFAM mRNA]; Resveratrol affects the reaction [Benzo(a)pyrene affects the expression of TFAM protein]; Resveratrol inhibits the reaction [Dietary Fats results in decreased expression of TFAM mRNA]; Resveratrol inhibits the reaction [Rotenone results in decreased expression of TFAM mRNA]; Resveratrol inhibits the reaction [Rotenone results in decreased expression of TFAM protein] | PMID:21632075 PMID:26770656 PMID:32619457 | TFAM | multiple interactions | ISO | Tfam (Mus musculus) | 6480464 | CTD | [lipopolysaccharide, E coli O55-B5 co-treated with Resveratrol] results in increased expression of TFAM mRNA; dorsomorphin inhibits the reaction [Resveratrol results in increased expression of TFAM mRNA]; tin protoporphyrin IX inhibits the reaction [[lipopolysaccharide, E coli O55-B5 co-treated with Resveratrol] results in increased expression of TFAM mRNA]; tin protoporphyrin IX inhibits the reaction [Resveratrol results in increased expression of TFAM mRNA] | PMID:17438283 PMID:24041027 | |
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