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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1552640
Species: Mus musculus
RGD Object: Gene
Symbol: Prkaca
Name: protein kinase, cAMP dependent, catalytic, alpha
Acc ID: CHEBI:27881
Term: resveratrol
Definition: A stilbenol that is stilbene in which the phenyl groups are substituted at positions 3, 5, and 4' by hydroxy groups.
Chemical ID: MESH:C059514
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Prkacamultiple interactionsISOPRKACA (Homo sapiens)6480464CTD[TNF protein co-treated with resveratrol] results in increased expression of PRKACA protein; PRKACA protein affects the reaction [[TNF protein co-treated with resveratrol] results in increased expression of SIRT1 protein]; PRKACA protein promotes the reaction [resveratrol results in increased degradation of SQSTM1 protein]; PRKACA protein promotes the reaction [resveratrol results in increased expression of SIRT1 protein]PMID:24145604 PMID:25943029
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