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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 11474
Species: Mus musculus
RGD Object: Gene
Symbol: Ucp3
Name: uncoupling protein 3 (mitochondrial, proton carrier)
Acc ID: CHEBI:27881
Term: resveratrol
Definition: A stilbenol that is stilbene in which the phenyl groups are substituted at positions 3, 5, and 4' by hydroxy groups.
Chemical ID: MESH:C059514
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ucp3increases expressionEXP 6480464CTDresveratrol results in increased expression of UCP3 mRNAPMID:18657603 PMID:19934007
Ucp3multiple interactionsEXP 6480464CTD[resveratrol co-treated with Quercetin co-treated with Phytic Acid] results in increased expression of UCP3 mRNA; PRKAA1 protein promotes the reaction [resveratrol results in increased expression of UCP3 mRNA]; PRKAA2 protein promotes the reaction [resveratrol results in increased expression of UCP3 mRNA]PMID:18657603 PMID:19934007
Ucp3increases expressionISOUcp3 (Rattus norvegicus)6480464CTDresveratrol results in increased expression of UCP3 proteinPMID:23790948
Ucp3multiple interactionsISOUcp3 (Rattus norvegicus)6480464CTDresveratrol inhibits the reaction [Dexamethasone results in increased expression of UCP3 mRNA]PMID:17884810
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