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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 11104
Species: Mus musculus
RGD Object: Gene
Symbol: Pim1
Name: proviral integration site 1
Acc ID: CHEBI:27881
Term: resveratrol
Definition: A stilbenol that is stilbene in which the phenyl groups are substituted at positions 3, 5, and 4' by hydroxy groups.
Chemical ID: MESH:C059514
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Pim1increases expressionISOPIM1 (Homo sapiens)6480464CTDresveratrol results in increased expression of PIM1 mRNA; resveratrol results in increased expression of PIM1 proteinPMID:27049278
Pim1multiple interactionsISOPIM1 (Homo sapiens)6480464CTD2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [resveratrol inhibits the reaction [Glucose results in decreased expression of PIM1 mRNA]]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [resveratrol inhibits the reaction [Glucose results in decreased expression of PIM1 protein]]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [resveratrol inhibits the reaction [Hydrogen Peroxide results in decreased expression of PIM1 mRNA]]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [resveratrol inhibits the reaction [Hydrogen Peroxide results in decreased expression of PIM1 protein]]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [resveratrol results in increased expression of PIM1 mRNA]; [resveratrol co-treated with 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one] results in decreased expression of PIM1 protein; resveratrol inhibits the reaction [Glucose results in decreased expression of PIM1 mRNA]; resveratrol inhibits the reaction [Glucose results in decreased expression of PIM1 protein]; resveratrol inhibits the reaction [Hydrogen Peroxide results in decreased expression of PIM1 mRNA]; resveratrol inhibits the reaction [Hydrogen Peroxide results in decreased expression of PIM1 protein]PMID:27049278
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