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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 62391
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Ddit3
Name: DNA-damage inducible transcript 3
Acc ID: CHEBI:27869
Term: chloroacetic acid
Definition: A chlorocarboxylic acid that is acetic acid carrying a 2-chloro substituent.
Chemical ID: MESH:C006972
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ddit3increases expressionISORGD:623966480464CTDchloroacetic acid results in increased expression of DDIT3 mRNA; chloroacetic acid results in increased expression of DDIT3 proteinPMID:25451595
Ddit3multiple interactionsISORGD:623966480464CTDAcetylcysteine inhibits the reaction [chloroacetic acid results in increased expression of DDIT3 protein]PMID:25451595
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