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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1303073
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Xbp1
Name: X-box binding protein 1
Acc ID: CHEBI:27869
Term: chloroacetic acid
Definition: A chlorocarboxylic acid that is acetic acid carrying a 2-chloro substituent.
Chemical ID: MESH:C006972
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Xbp1increases expressionISORGD:13323126480464CTDchloroacetic acid results in increased expression of XBP1 mRNA alternative form; chloroacetic acid results in increased expression of XBP1 protein alternative formPMID:25451595
Xbp1multiple interactionsISORGD:13323126480464CTDAcetylcysteine inhibits the reaction [chloroacetic acid results in increased expression of XBP1 protein alternative form]PMID:25451595
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