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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 736022
Species: Mus musculus
RGD Object: Gene
Symbol: App
Name: amyloid beta precursor protein
Acc ID: CHEBI:278547
Term: sodium azide
Definition: The sodium salt of hydrogen azide (hydrazoic acid).
Chemical ID: MESH:D019810
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Appincreases expressionISOApp (Rattus norvegicus)6480464CTDSodium Azide results in increased expression of APP proteinPMID:36249784
Appmultiple interactionsISOApp (Rattus norvegicus)6480464CTD2,2-bis(4-glycidyloxyphenyl)propane affects the reaction [bergenin affects the reaction [Sodium Azide results in increased expression of APP protein]]; bergenin affects the reaction [Sodium Azide results in increased expression of APP protein]PMID:36249784
Appmultiple interactionsISOAPP (Homo sapiens)6480464CTD[Sodium Azide co-treated with Deoxyglucose] affects the cleavage of and affects the localization of APP protein; Sodium Azide inhibits the reaction [Adenosine Triphosphate results in increased secretion of APP protein modified form]PMID:17405930 PMID:22906069
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