GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Casp3 | increases activity | EXP | | 6480464 | CTD | Paraoxon results in increased activity of CASP3 protein | PMID:17561261 | Casp3 | increases expression | EXP | | 6480464 | CTD | Paraoxon results in increased expression of CASP3 mRNA; Paraoxon results in increased expression of CASP3 protein | PMID:31493121 | Casp3 | multiple interactions | EXP | | 6480464 | CTD | Ro 31-8220 inhibits the reaction [Paraoxon results in increased activity of CASP3 protein] | PMID:17561261 | Casp3 | increases activity | ISO | CASP3 (Homo sapiens) | 6480464 | CTD | Paraoxon results in increased activity of CASP3 protein | PMID:11032765 | Casp3 | multiple interactions | ISO | Casp3 (Mus musculus) | 6480464 | CTD | benzyloxycarbonyl-leucyl-glutamyl-histidyl-aspartic acid fluoromethyl ketone inhibits the reaction [Paraoxon results in increased cleavage of and results in increased activity of CASP3 protein]; benzyloxycarbonyl-valyl-alanyl-aspartyl-fluoromethane analog inhibits the reaction [Paraoxon results in increased cleavage of and results in increased activity of CASP3 protein]; Egtazic Acid inhibits the reaction [Paraoxon results in increased expression of and affects the activity of CASP3 protein]; Heparin inhibits the reaction [Paraoxon results in increased expression of and affects the activity of CASP3 protein]; Metoclopramide inhibits the reaction [Paraoxon results in increased activity of and results in increased cleavage of CASP3 protein]; Paraoxon results in increased activity of and results in increased cleavage of CASP3 protein; Paraoxon results in increased cleavage of and results in increased activity of CASP3 protein; Paraoxon results in increased expression of and affects the activity of CASP3 protein; Procaine inhibits the reaction [Paraoxon results in increased expression of and affects the activity of CASP3 protein] | PMID:12831782 PMID:26998625 PMID:29027213 | Casp3 | multiple interactions | ISO | CASP3 (Homo sapiens) | 6480464 | CTD | Cyclosporine inhibits the reaction [Paraoxon results in increased activity of CASP3 protein] | PMID:11032765 | |
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