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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1352582
Species: Homo sapiens
RGD Object: Gene
Symbol: IL6
Name: interleukin 6
Acc ID: CHEBI:27827
Term: paraoxon
Definition: An aryl dialkyl phosphate where both the alkyl groups are ethyl and the aryl group is 4-nitrophenyl.
Chemical ID: MESH:D010261
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
IL6decreases expressionISOIl6 (Mus musculus)6480464CTDParaoxon results in decreased expression of IL6 mRNAPMID:22093924
IL6increases expressionISOIl6 (Rattus norvegicus)6480464CTDParaoxon results in increased expression of IL6 proteinPMID:34778934
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