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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2729
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Gpx1
Name: glutathione peroxidase 1
Acc ID: CHEBI:27812
Term: Se-methyl-L-selenocysteine
Definition: An L-alpha-amino acid compound having methylselanylmethyl as the side-chain.
Chemical ID: MESH:C002979
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Gpx1increases activityISORGD:7370056480464CTDselenomethylselenocysteine results in increased activity of GPX1 proteinPMID:19033020
Gpx1increases expressionISORGD:7370056480464CTDselenomethylselenocysteine results in increased expression of GPX1 mRNA; selenomethylselenocysteine results in increased expression of GPX1 proteinPMID:18514395 PMID:19033020
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