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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1562895
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Hdac8
Name: histone deacetylase 8
Acc ID: CHEBI:27812
Term: Se-methyl-L-selenocysteine
Definition: An L-alpha-amino acid compound having methylselanylmethyl as the side-chain.
Chemical ID: MESH:C002979
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Hdac8multiple interactionsISOHDAC8 (Homo sapiens)6480464CTDHDAC8 inhibits the reaction [selenomethylselenocysteine metabolite results in increased expression of BMF mRNA]; selenomethylselenocysteine metabolite inhibits the reaction [HDAC8 protein binds to BMF promoter]PMID:25321483
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