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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 735878
Species: Homo sapiens
RGD Object: Gene
Symbol: ACHE
Name: acetylcholinesterase (Yt blood group)
Acc ID: CHEBI:27789
Term: 1,2-dichloroethane
Definition: A member of the class of chloroethanes substituted by two chloro groups at positions 1 and 2.
Chemical ID: MESH:C024565
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
ACHEdecreases activityISOAche (Rattus norvegicus)6480464CTDethylene dichloride results in decreased activity of ACHE proteinPMID:14631503 PMID:24228488
ACHEmultiple interactionsISOAche (Rattus norvegicus)6480464CTDazoximer bromide inhibits the reaction [ethylene dichloride results in decreased activity of ACHE protein]PMID:24228488
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