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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 10230
Species: Mus musculus
RGD Object: Gene
Symbol: Bcl2
Name: B cell leukemia/lymphoma 2
Acc ID: CHEBI:27789
Term: 1,2-dichloroethane
Definition: A member of the class of chloroethanes substituted by two chloro groups at positions 1 and 2.
Chemical ID: MESH:C024565
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Bcl2decreases expressionEXP 6480464CTDethylene dichloride results in decreased expression of BCL2 mRNA; ethylene dichloride results in decreased expression of BCL2 proteinPMID:28973639 PMID:34560092
Bcl2increases expressionEXP 6480464CTDethylene dichloride results in increased expression of BCL2 mRNAPMID:28960355
Bcl2decreases expressionISOBCL2 (Homo sapiens)6480464CTDethylene dichloride results in decreased expression of BCL2 mRNA; ethylene dichloride results in decreased expression of BCL2 proteinPMID:34560092
Bcl2multiple interactionsISOBCL2 (Homo sapiens)6480464CTD[Antagomirs results in decreased expression of MIR182 mRNA] inhibits the reaction [ethylene dichloride results in decreased expression of BCL2 mRNA]; [Antagomirs results in decreased expression of MIR182 mRNA] inhibits the reaction [ethylene dichloride results in decreased expression of BCL2 protein]PMID:34560092
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