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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 735711
Species: Homo sapiens
RGD Object: Gene
Symbol: CYP1A2
Name: cytochrome P450 family 1 subfamily A member 2
Acc ID: CHEBI:27779
Term: griseofulvin
Definition: An oxaspiro compound produced by Penicillium griseofulvum. It is used by mouth as an antifungal drug for infections involving the scalp, hair, nails and skin that do not respond to topical treatment.
Chemical ID: MESH:D006118
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
CYP1A2multiple interactionsEXP 6480464CTDGriseofulvin promotes the reaction [CYP1A2 protein affects the metabolism of Theophylline]PMID:9029748
CYP1A2affects expressionISOCyp1a2 (Mus musculus)6480464CTDGriseofulvin affects the expression of CYP1A2 mRNAPMID:12735108
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