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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 735404
Species: Homo sapiens
RGD Object: Gene
Symbol: ALB
Name: albumin
Acc ID: CHEBI:27744
Term: glyphosate
Definition: A phosphonic acid resulting from the formal oxidative coupling of the methyl group of methylphosphonic acid with the amino group of glycine. It is one of the most commonly used herbicides worldwide, and the only one to target the enzyme 5-enolpyruvyl-3-shikimate phosphate synthase (EPSPS).
Chemical ID: MESH:C010974
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
ALBaffects bindingEXP 6480464CTDGlyphosate binds to ALB proteinPMID:18035550
ALBaffects expressionISOAlb (Mus musculus)6480464CTDGlyphosate affects the expression of ALB proteinPMID:20045496
ALBincreases expressionISOAlb (Rattus norvegicus)6480464CTDGlyphosate results in increased expression of ALB mRNA; Glyphosate results in increased expression of ALB proteinPMID:25067936 PMID:26302742
ALBmultiple interactionsISOAlb (Rattus norvegicus)6480464CTDZinc inhibits the reaction [Glyphosate results in increased expression of ALB protein]PMID:25067936
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