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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 68949
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Il13
Name: interleukin 13
Acc ID: CHEBI:27744
Term: glyphosate
Definition: A phosphonic acid resulting from the formal oxidative coupling of the methyl group of methylphosphonic acid with the amino group of glycine. It is one of the most commonly used herbicides worldwide, and the only one to target the enzyme 5-enolpyruvyl-3-shikimate phosphate synthase (EPSPS).
Chemical ID: MESH:C010974
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Il13increases expressionISOIl13 (Mus musculus)6480464CTDGlyphosate results in increased expression of IL13 proteinPMID:25172162
Il13multiple interactionsISOIl13 (Mus musculus)6480464CTDIL13 protein affects the reaction [Glyphosate results in increased expression of IL33 protein]; IL13 protein affects the reaction [Glyphosate results in increased expression of IL5 protein]; IL13 protein affects the reaction [Glyphosate results in increased expression of TSLP protein]PMID:25172162
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